About This Surgery

This operation is adapted from a variation of sleeve and bypass performed by Dr. Santoro. It is understood to combine the benefits of sleeve and bypass.

A sleeve gastrectomy is performed and then a loop of small bowel is connected to the sleeved stomach. Food has two pathways to leave the stomach, the normal way through the duodenum, and a shorter pathway into the bypassed bowel. There is less nutritional deficiency risk for these patients in the future. The potential exists to reverse the bypass component. The loop of bowel could be disconnected if patients have bad bowel symptoms. It significantly alters the hunger and fullness hormones.

Key Facts

Expected Excess Weight Loss

60-80%

Primary or Revisional

Primary or Revisional

Recovery

2 weeks

Is robotic surgery an option

Yes

Advantages

  • Technically easier to perform so it lowers operative risk: The simplified surgical procedure reduces the complexity and duration of the operation, minimizing potential complications.
  • Weight loss benefits without significant nutritional risk: It effectively limits food intake and absorption while maintaining essential nutrient absorption, reducing the likelihood of deficiencies.
  • Duodenum and Bile duct accessible for future gallstone issues: The preserved anatomy allows for non-invasive endoscopic access to the bile duct, facilitating easier management of gallstones.
  • Lowers bad cholesterol and elevates good cholesterol: This procedure positively affects lipid metabolism, helping decrease LDL (bad cholesterol) and increase HDL (good cholesterol) levels.
  • Reduces insulin levels: It enhances insulin sensitivity and promotes better glucose control, which is particularly beneficial for patients with type 2 diabetes.
  • Bypass REVERSIBLE if bowel symptoms or dumping severe: If severe side effects occur, the surgical alterations can be reversed, restoring normal bowel function and alleviating symptoms.
weight loss surgery

Disadvantages

  • Short follow-up data: Limited long-term data on outcomes and potential complications makes it challenging to fully understand the enduring effects of the procedure.
  • Anastomosis risk: The surgical connection between the stomach and intestine (anastomosis) carries a risk of leakage or stricture, which can lead to serious complications.
  • Mild reflux possible: Patients may experience mild gastroesophageal reflux disease (GORD) post-surgery due to changes in the stomach's anatomy and pressure dynamics.
  • Internal hernia risk: The surgery can create spaces in the abdominal cavity where the intestine might get trapped, leading to an internal hernia, which can cause pain and obstruction.

Is this right for me?

  • BMI: RNYGB is a revisional option for patients who have regained significant weight after a sleeve or gastric band and have significant reflux.
  • Health conditions: Obesity-related conditions like DM Type 2, high blood pressure, sleep apnoea.
  • Previous weight loss attempts: Tried and failed to lose weight through diet, exercise, medications and previous surgery.
  • Commitment to Lifestyle changes. RNYGB is a tool, it requires a commitment to long-term lifestyle changes including dietary changes and regular physical activity.
  • Medical/Surgical History: You will be evaluated to determine if you're a suitable candidate.
  • Risks and Benefits: Risks and benefits and alternative treatment options will be discussed.

It’s crucial to have an open and honest discussion with your healthcare provider to determine if SASI-S is the right choice for you based on your circumstances, preferences and goals

Surgery FAQs

What is Single Anastomosis Stomach Ileal Bypass with Sleeve Gastrectomy (SASI-S)?

Single Anastomosis Stomach Ileal Bypass with Sleeve Gastrectomy (SASI-S) is a bariatric surgery that combines sleeve gastrectomy with a single anastomosis stomach-ileal bypass, reducing stomach size and rerouting the digestive tract to promote weight loss.

How does SASI-S differ from other bariatric surgeries like gastric bypass or sleeve gastrectomy?

SASI-S differs from other bariatric surgeries by combining restrictive and malabsorptive components, resulting in significant weight loss and metabolic changes. It offers a simpler surgical technique compared to procedures like gastric bypass while providing similar weight loss outcomes.

What are the potential benefits of SASI-S compared to other weight loss surgeries?

Potential benefits of SASI-S include significant and sustained weight loss, improvement or resolution of obesity-related health conditions such as type 2 diabetes and hypertension, and reduced risk of dumping syndrome compared to gastric bypass.

What is the procedure for SASI-S, and how is it performed?

During SASI-S, a portion of the stomach is removed to create a smaller sleeve-shaped stomach, and the small intestine is rerouted to bypass a section of the digestive tract. This limits food intake and reduces nutrient absorption, aiding in weight loss.

What is the expected weight loss after undergoing SASI-S?

Expected weight loss after SASI-S varies but can often result in around 60-80% excess weight loss within the first year after surgery, with continued weight loss over time with adherence to lifestyle changes.

Are there any potential risks or complications associated with SASI-S surgery?

Potential risks and complications associated with SASI-S surgery include infection, bleeding, leaks at the surgical sites, nutritional deficiencies, and gastrointestinal issues. However, these risks are generally lower compared to more complex procedures like duodenal switch.

How long is the recovery period after SASI-S surgery, and what should I expect during the recovery process?

The recovery period after SASI-S surgery typically ranges from several weeks to months, with patients gradually resuming normal activities under medical supervision. Patients may experience discomfort, dietary changes, and follow-up appointments to monitor progress.

Will I need to make significant lifestyle changes or follow a special diet after SASI-S surgery?

After SASI-S surgery, patients need to make significant lifestyle changes, including adopting a healthy diet rich in protein and nutrients, regular exercise, and attending follow-up appointments with healthcare providers.

What type of patients are suitable candidates for SASI-S surgery?

Suitable candidates for SASI-S surgery are individuals with severe obesity (BMI ≥ 40) with obesity-related health conditions, who have not achieved weight loss with other methods and are committed to making lifelong dietary and lifestyle changes.

Are the results of SASI-S surgery permanent, or can weight regain occur over time?

The results of SASI-S surgery can be permanent with proper adherence to lifestyle changes. However, weight regain can occur over time if dietary and exercise habits are not maintained, highlighting the importance of ongoing support and follow-up care.

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